Tuguegarao is a 2nd-class city and capital of the province of Cagayan in the Philippines. It is the regional and institutional center of Cagayan Valley region.

The city is located on a peninsula surrounded by the Cagayan and Pinacanauan Rivers. The Pinacanauan joins the Cagayan River in Tuguegarao. The city is surrounded by the Sierra Madre Mountains to the east, Cordillera Mountains to the west, and the Caraballo Mountains to the south. It is one of the settlements on the southern border of the province.

The population of the city as of the May 1, 2010 census is 138,865 people. Most inhabitants are Ibanag, Ilokano, Tagalog, Itawes and Kapamapangan among others. Some are of Chinese and Indian descent.
The highest temperature in the Philippines was recorded in Tuguegarao on April 29, 1912, and May 11, 1969, at 42.2 °C (108.0 °F). Average temperature during March and April is 38 °C (100 °F), one of the highest in the country.